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Trimethoprim for klebsiella uti and the Pyrimethamine group (including metronidazole). majority of the patients were admitted to hospital with pneumonia. A total of 4 patients were treated with azithromycin. This may be due to the high frequency and low severity of the infection in this group. majority of the patients with klebsiella pneumonia were treated the combination of clindamycin and metronidazole. In addition, a significant proportion of patients with klebsiella pneumonia were prescribed metronidazole for their acute disease; however, the duration of treatment was limited and most patients were discharged home. We performed a sensitivity analysis of the use other non-classical antibacterial drugs, including clarithromycin, erythromycin, mupirocin, and gentamicin. We performed these analyses with and without treatment clindamycin, metronidazole trimethoprim. As shown in the Figure 3, this approach resulted in a substantial increase sensitivity and specificity for clinical infection with klebsiella pneumonia in the trimethoprim group compared to clindamycin (P < 0.0001 and P 0.0001, Buy modafinil wholesale respectively). We also performed these analyses for other antibiotics and their combination with clindamycin, metronidazole, and trimethoprim. For patients with klebsiella pneumonia, treatment metronidazole alone resulted in a significantly reduced risk of clinical infection compared to treatment with generic drug prices canada vs us clindamycin. However, trimethoprim alone resulted in an increased risk of infection compared to clindamycin. It should be noted that in both of these sensitivity analyses, the risk of infection was significantly associated with the Ambien 5mg 30 $110.00 $3.67 antibiotic combination in clindamycin (P < 0.0001). Therefore, the combination of clindamycin, metronidazole, and trimethoprim appears to provide adequate protection against klebsiella is there an over the counter medicine similar to ambien pneumonia in clinical practice. Figure 3 View largeDownload slide Risk of clinical infection in combination with clindamycin, metronidazole, and trimethoprim compared to clindamycin with metronidazole (n = 4). The results of sensitivity analyses trimethoprim versus the combination of clindamycin and metronidazole indicated that, overall, the risk of infection with klebsiella pneumonia was not significantly different in the trimethoprim group compared to combination of clindamycin and metronidazole. The number needed to treat is presented in Table 2 with the corresponding risk ratios for patient with klebsiella pneumonia in combination clindamycin and metronidazole. The risk ratios for patient with klebsiella pneumonia in combination either clindamycin or metronidazole were not significantly different compared to those for the patient with klebsiella pneumonia in combination metronidazole (Table 2). In the absence of metronidazole, combination clindamycin and trimethoprim resulted in reduced bacterial counts over time. There was no evidence of bacteriological compromise when both clindamycin and trimethoprim were combined at a dose of 1 g/L. Clindamycin had no effect on the level of klebsiella in this group. At a dose of 0.5 g/L, further 50 g metronidazole was required to achieve bacteriostatic effect. Table 2. Drug Combination No. of Patients (N = 23) Risk of klebsiella infection (95% CI)a No of Patients (N = 23) Risk of klebsiella infection (95% CI)a Clindamycin (N = 3) 0.5 (0.2–0.9) 1.0 (0.5–1.9) Metronidazole (N = 3) 1.0 (0.5–1.8) 0.9 (0.5–1.5) Clindamycin (N = 2) 1.0 (0.6–1.6) 0.7 (0.3–1.1) Metronidazole (N = 2) 0.5 (0.2–1.0) 1.0 (0.6–1.9) Clindamycin (N = 2) 1.0 (0.5–1.8) 0.8 (0.3–1.4) Metronidazole (N = 2) 0.7 (0)

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